RS-22A, B and C: new macrolide antibiotics from Streptomyces violaceusniger. I. Taxonomy, fermentation, isolation and biological activities.

نویسندگان

  • M Ubukata
  • N Shiraishi
  • K Kobinata
  • T Kudo
  • I Yamaguchi
  • H Osada
  • Y C Shen
  • K Isono
چکیده

Three novel 36-membered macrolide antibiotics, RS-22A, B and C produced by Streptomyces violaceusniger have been isolated. These antibiotics were purified from an acetone extract of the mycelia followed by butanol extraction, centrifugal partition chromatography and HPLC. RS-22A, B, C showed antimicrobial activity against fungi and Gram-positive bacteria.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 48 4  شماره 

صفحات  -

تاریخ انتشار 1995